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KMID : 0363219940320020245
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Korean Journal of Dermatology
1994 Volume.32 No. 2 p.245 ~ p.252
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A Clinical and Histopathologic Study of Livedo Vasculitis
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Abstract
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Background:
@EN Livedo vasculitis shows variable clinical and histopathologic features according to its courses. Three are also some discrepancies in histopathologic findings between the authors.
@ES Objective:
@EN Our purpose is to clarify the clinical and histopathologic features of livedo vasculitis.
@ES Methods:
@EN We reviewed the clinical and histopathologic features including direct immunofluorescence study and response to treatment in eight patients with livedo vasculitis.
@ES Results:
@EN The ratio of males to females was 1 : 3 with female predominance. Age of onset was predominant in young to middle-age, ranging from 19 to 64 years old. In seven patients skin lesions were aggravated during the summer, and in one patient
during
the
winter. All patients had purpuric or telangiectatic lesions on the lower extremities. Painful ulcers developed in seven patients and some of the ulcers healed with whitish atrophic scars. Five patients did not abnormal findings related to the
systemic
disease. Histopathologically, in two patients fibrinoid material was deposited in the vessel walls mildly, and in six patients obviously with partial to complete obstruction of blood vesels. Extravasation of RBCs and thrombus formation were found
clearly in seven patients, but in one patient these findings were observed in a mild degree. Endothelial swellings were observed in all patients. Perivascular infiltrations of mononuclear cells were also observed in all patients in various
degrees.
But
only two patients with secondary bacterial infection showed neutrophil infiltrations or nuclear dusts. So, histopathologic findings are compatible with lymphocytic vasculitis. The locations of predominantly affected vessels were variable. Direct
immunofluorescence studies were done in six patients. Four of these patients showed positive findings. At least 4 months were needed for the complete healing of the skin lesions.
@ES Conclusion:
@EN Livedo vasculitis in chronic vasculitis aggravated in mostly summer. Most of the initial purpuric lesions progress to ulcers which is healed with whitish atrophic scars. Histopathologic findings suggest livedo vasculitis is a sort of
lymphocytic
vasculitis. (Kor J Dermatol 1994 ; 32(2) : 245~252).
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